منابع مشابه
The Site of Angiotonin Destruction
1. Theoretical considerations render it unlikely that the greatest part of the angiotonase found in the organism is available for the destruction of angiotonia. A priori considerations support the view that only plasma angiotonase is involved in angiotonin destruction in vivo. 2. We have utilized the magnitude and duration of the presser response to angiotonin as an index of available angiotona...
متن کاملAngiotonin-activator, Renin- and Angiotonin-inhibitor, and the Mechanism of Angiotonin Tachyphylaxis in Normal, Hypertensive, and Nephrectomized Animals
1. Angiotonin does not exert its vasoconstrictor effect in the absence of a substance contained in red blood cells and serum which we have called "angiotonin-activator." A fraction has been separated from blood in which angiotonin-activator is concentrated. It contains little or no reninactivator. 2. Repeated intravenous injections of angiotonin into animals causes the pressor response graduall...
متن کاملPharmacologic aspects of synthetic angiotonin.
Tho. synthetic octapeptide angiotonin evoked systolic and diastolic pressure responses in anesthetized and unanesthetized dogs identical with those due to a natural, largely decapeptide, angiotonin, and responses to both angiotonins were modified in the same manner by a variety of procedures. Infusion of synthetic angiotonin caused hypertension sustained for the durations of the infusions and t...
متن کاملSynthesis and properties of angiotonin.
ANGIOTONIN (hypertensin) was discovered in 1939, but it was not until 1956 that its structure was reported. In 1954 we published an amino acid analysis and a determination of the end amino acids of angiotonin. We know now that the preparation used was about 75 per cent pure, which accounts for the additional amino acids reported; the end amino acids were later shown to be correct. During the pu...
متن کاملthe effect of taftan pozzolan on the compressive strength of concrete in the environmental conditions of oman sea (chabahar port)
cement is an essential ingredient in the concrete buildings. for production of cement considerable amount of fossil fuel and electrical energy is consumed. on the other hand for generating one tone of portland cement, nearly one ton of carbon dioxide is released. it shows that 7 percent of the total released carbon dioxide in the world relates to the cement industry. considering ecological issu...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1954
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1954.tb00839.x